• Neurocritical care · Apr 2012

    Case Reports

    Acute epidural spinal hemorrhage from vasculitis: resolution with immunosuppression.

    • Jeffrey T Jacob, Shota Tanaka, Christopher P Wood, Eelco F Wijdicks, and Giuseppe Lanzino.
    • Department of Neurologic Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. jacob.jeffrey@mayo.edu
    • Neurocrit Care. 2012 Apr 1;16(2):311-5.

    BackgroundAngiographic vasculitis affecting the spine has been rarely described. The use of immunosuppression as a primary treatment and a review of the literature is presented.MethodsCase report.ResultsA 61-year-old female presented with sudden onset back pain and headache. The patient was found to have acute spinal epidural hemorrhage and subsequent work-up demonstrated angiographic spinal vasculitis. Immunosuppression with cyclophosphamide resulted in clinical and radiographic improvement.ConclusionsImmunomodulating therapy should be considered in the management of select patients with spinal vasculitis which may lead to improved clinical outcome and potentially disease resolution.

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