• J Neurosurg Anesthesiol · Jan 2002

    Effect of sevoflurane on electrocorticogram in normal brain.

    • Kiyotaka Sato, Hiroshi Shamoto, and Masato Kato.
    • Department of Neuroanesthesia, Kohnan Hospital, Sendai, Japan.
    • J Neurosurg Anesthesiol. 2002 Jan 1;14(1):63-5.

    AbstractTo clarify the epileptogenicity of sevoflurane, electrocorticograms were monitored in seven patients with unruptured cerebral aneurysm under sevoflurane anesthesia. They had no history of epilepsy or other complications. Spike activities on electrocorticography were seen in all seven patients at 3.3% end-tidal sevoflurane. These results suggest that further study is required to evaluate the suitability of sevoflurane for neurosurgical procedures.

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