• Shigefumi Matsuyama, Minoru Tabata, Tomoki Shimokawa, Akihito Matsushita, Toshihiro Fukui, and Shuichiro Takanashi.
• Department of Cardiovascular Surgery, Sakakibara Heart Institute, Tokyo, Japan.
• J. Thorac. Cardiovasc. Surg. 2012 Jun 1;143(6):1377-81.

ObjectiveTotal arch replacement has been reported to present high morbidity and mortality. We have introduced a stepwise distal anastomosis technique and modified perfusion strategy, including selective antegrade cerebral perfusion, moderate hypothermia, and separate lower-body perfusion, to minimize organ ischemia and secondary morbidities. We report the operative outcomes of total arch replacement with our modified perfusion strategy.MethodsBetween August 2006 and December 2008, 119 patients underwent total arch replacement with the current perfusion strategy. Of these patients, 56 (47%) underwent emergency operation for acute type A aortic dissection (n = 48) or ruptured thoracic aneurysm (n = 8). The mean age of patients was 68 years, and the mean follow-up period was 25 months. We analyzed operative mortality, morbidity, and 4-year survival of this patient group.ResultsThe mean operation, cardiopulmonary bypass, and circulatory arrest times were 313, 183, and 47 minutes, respectively. Operative mortality was 3.4%. Operative mortality of elective cases was 1.6%. The incidences of permanent neurologic deficit, paraparesis, and renal insufficiency were 5.0%, 1.7%, and 7.6%, respectively. Actuarial 4-year survival was 86.5%.ConclusionsTotal arch replacement with our modified perfusion strategy has demonstrated low operative mortality and morbidity.Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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