• Clinics in perinatology · Jun 2012

    Review

    Advances in neonatal extracorporeal support: the role of extracorporeal membrane oxygenation and the artificial placenta.

    • Brian W Gray, Andrew W Shaffer, and George B Mychaliska.
    • Section of Pediatric Surgery, C.S. Mott Children's Hospital, University of Michigan Health System, B560 MSRBII, 1150 West Medical Center Drive, Ann Arbor, MI 48109, USA.
    • Clin Perinatol. 2012 Jun 1;39(2):311-29.

    AbstractThis review addresses the history and evolution of neonatal extracorporeal membrane oxygenation (ECMO), with a discussion of the indications, contraindications, modalities, outcomes, and impact of ECMO. Controversies surrounding novel uses of ECMO in neonates, namely ECMO for premature infants and ex utero intrapartum therapy with transition to ECMO, are discussed. The development of an extracorporeal artificial placenta for support of premature infants is presented, including the rationale, research, and challenges. ECMO has had a dramatic effect on the care of critically ill neonates over the past 4 decades, and there is great potential to expand these benefits in the future.Copyright © 2012 Elsevier Inc. All rights reserved.

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