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- Kenta Okamura, Michiyoshi Sanuki, Hiroyuki Kinoshita, Kiyoshi Fujii, and Aki Matsunaga.
- Department of Anesthesia and Intensive Care, Hiroshima City Asa Hospital, Hiroshima 730-0293.
- Masui. 2003 Nov 1;52(11):1181-5.
BackgroundSerious side effects of postoperative analgesia with opioid drugs include nausea and vomiting.MethodsWe investigated the effects of various factors (patient background, anesthesia duration, and intraoperative drug use) on the frequency and degree of postoperative nausea and vomiting (PONV) during the first 24 hours of intravenous patient-controlled analgesia (PCA) with fentanyl.ResultsPONV occurred in 34% of the male patients and 68% of the female, and in 31% and 58% of smokers and non-smokers, respectively.ConclusionsConsideration should be given to gender and smoking status prior to starting preventive antiemetic therapy using PCA with fentanyl following cervical spine surgery.
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