• Yoko Miyasaka, Satoshi Tsujimoto, Hirofumi Maeba, Fumio Yuasa, Kazuya Takehana, Kinuko Dote, and Toshiji Iwasaka.
• Cardiovascular Division, Department of Medicine II, Kansai Medical University, 2-3-1 Shin-machi, Hirakata, Japan. miyasaka@hirakata.kmu.ac.jp
• J Am Soc Echocardiogr. 2011 Jun 1;24(6):680-6.

BackgroundLeft atrial (LA) enlargement has been acknowledged as a significant predictor of cardiovascular morbidity and mortality.MethodsTo evaluate the accuracy of two-dimensional and three-dimensional echocardiography for determining LA volume, LA volume measurements by echocardiography were compared with those measured by 64-slice multidetector computed tomography (MDCT) as a reference standard.ResultsFifty-seven consecutive patients (mean age, 66 ± 11 years; 59% men) referred to echocardiography and MDCT on the same day were prospectively evaluated. LA volume by three-dimensional echocardiography was correlated closely with that by MDCT (r = 0.95, P < .0001), with 8% underestimation. LA volume by two-dimensional echocardiography was correlated less well with that measured by MDCT (r = 0.86, P < .0001) and consistently underestimated LA volume by 19%, particularly as the left atrium enlarged.ConclusionsLA volume assessment by three-dimensional echocardiography was correlated closely with that measured by MDCT, albeit with an 8% underestimation. Three-dimensional echocardiography is a feasible noninvasive method to evaluate LA volume.Copyright © 2011 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved.

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