• Acta Anaesthesiol Scand · Nov 2008

    Randomized Controlled Trial Comparative Study

    Caudal midazolam does not affect sevoflurane requirements and recovery in pediatric day-case hernioplasty.

    • J-Y Hong, I H Lee, S K Shin, E Y Park, S Y Ban, J E Cho, and H K Kil.
    • Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Severance Hospital, Yonsei University College of Medicine, Seodaemun-Gu, Seoul, Korea. jenyhongg@hanmail.net
    • Acta Anaesthesiol Scand. 2008 Nov 1;52(10):1411-4.

    BackgroundThis prospective, randomized, double-blind study aimed to determine whether caudal midazolam combined with ropivacaine affects anesthetic requirements, recovery profiles, and post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty.MethodsSixty boys (2-5 years old) received caudal injections of 0.2% ropivacaine 1 ml/kg and epinephrine 1 : 200,000 with (RM group) or without (R group) 50 microg/kg of midazolam under sevoflurane anesthesia. The sevoflurane requirement was determined by adjusting to a bispectral index score=50.ResultsConcentrations of end-tidal sevoflurane (ETsevo%) after induction were similar in both groups. After caudal block, ETsevo% before and after surgical stimuli did not show significant intra- or intergroup differences. Recovery characteristics, including post-operative sedations, were similar in both groups. Post-operative pain scores were significantly lower in the RM group than the R group.ConclusionsCaudal midazolam (50 microg/kg) added to 2% ropivacaine did not influence sevoflurane requirement or recovery but improved post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty.

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