• Clinics in perinatology · Sep 2013

    Review

    Sedation and analgesia to facilitate mechanical ventilation.

    • Michael E Nemergut, Myron Yaster, and Christopher E Colby.
    • Department of Anesthesiology, The Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA. nemergut.michael@mayo.edu
    • Clin Perinatol. 2013 Sep 1;40(3):539-58.

    AbstractRegardless of age, health care professionals have a professional and ethical obligation to provide safe and effective analgesia to patients undergoing painful procedures. Historically, newborns, particularly premature and sick infants, have been undertreated for pain. Intubation of the trachea and mechanical ventilation are ubiquitous painful procedures in the neonatal intensive care unit that are poorly assessed and treated. The authors review the use of sedation and analgesia to facilitate endotracheal tube placement and mechanical ventilation. Controversies regarding possible adverse neurodevelopmental outcomes after sedative and anesthetic exposure and in the failure to treat pain is also discussed.Copyright © 2013 Elsevier Inc. All rights reserved.

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