• Respiratory care · Jun 2013

    Review

    Sedation and paralysis.

    • Annop Piriyapatsom, Edward A Bittner, Jessica Hines, and Ulrich H Schmidt.
    • Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts 02115, USA.
    • Respir Care. 2013 Jun 1;58(6):1024-37.

    AbstractSedation is used almost universally in the care of critically ill patients, especially in those who require mechanical ventilatory support or other life-saving invasive procedures. This review will focus on the sedation strategies for critically ill patients and the pharmacology of commonly used sedative agents. The role of neuromuscular blocking agents in the ICU will be examined and the pharmacology of commonly used agents is reviewed. Finally a strategy for rational use of these sedative and neuromuscular blocking agents in critically ill patients will be proposed.

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