• Natalie Gray and Michael Vloeberghs.
• Queens Medical Centre, Nottingham University Hospital, Nottingham, UK. Electronic address: natalie.gray@nuh.nhs.uk.
• Eur. J. Paediatr. Neurol. 2014 Jan 1;18(1):45-9.

AimTo investigate the effect of intrathecal baclofen (ITB) on sitting in children with cerebral palsy with severe spasticity; and identify potential sub-groups of patients at particular risk of deterioration.MethodTwenty three children with cerebral palsy, mean age 10 yrs 10 mo were assessed before and after ITB treatment using the Sitting dimension of the Gross Motor Function Measure. Sitting prior to treatment was compared to sitting following ITB treatment in the same children. Exploration of sub groups was also attempted to investigate affects of ITB on sitting according to age and severity of motor impairment.ResultsNo significant difference was found in sitting before ITB treatment compared to sitting following insertion of an ITB pump (p = 0.09). No specific age group or classification of motor impairment demonstrated significant deterioration in sitting following ITB treatment.ConclusionSitting does not improve or deteriorate in children following treatment with ITB, independent of age or severity of motor impairment.Copyright © 2013 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

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