• Eur J Cardiothorac Surg · Sep 2008

    Case Reports

    Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenation.

    • Richard P Chalwin, Ravindranath Tiruvoipati, and Giles J Peek.
    • Department of ECMO, Glenfield Hospital, Leicester, LE3 9QP, UK.
    • Eur J Cardiothorac Surg. 2008 Sep 1;34(3):685-6.

    AbstractBleeding remains a potential complication for patients requiring extracorporeal life support systems. Recombinant activated factor VII (rFVIIa) is one of the drugs used in controlling bleeding. Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors that lead to fatal thrombosis.

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