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Semin. Thorac. Cardiovasc. Surg. · Jan 2005
Review Comparative StudyAntifibrinolytic agents in cardiac surgery: current controversies.
- Daniel L Serna, Vinod H Thourani, and John D Puskas.
- Carlyle Fraser Heart Center, Division of Cardiothoracic Surgery, Joseph B. Whitehead Department of Surgery, Emory University School of Medicine, Atlanta, GA 30308, USA.
- Semin. Thorac. Cardiovasc. Surg. 2005 Jan 1;17(1):52-8.
AbstractAntifibrinolytic agents play a prominent role in adult cardiac surgery. This article is a review of the modern published experience of antifibrinolytic agent use in adult cardiac surgery. The use of tranexamic acid, epsilon-aminocaproic acid, and aprotinin is examined during primary cardiac surgery, deep hypothermic circulatory arrest, reoperative cardiac surgery, and off-pump coronary artery bypass surgery. In addition, the issues of vein graft patency and hypersensitivity reaction in the presence of antifibrinolytic agents are examined.
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