• Clinics in perinatology · Sep 2012

    Review

    Synchronized mechanical ventilation using electrical activity of the diaphragm in neonates.

    • Howard Stein, Kimberly Firestone, and Peter C Rimensberger.
    • Department of Neonatology, Toledo Children's Hospital, 2142 North Cove Boulevard, Toledo, OH 43606, USA. Howardstein@bex.net
    • Clin Perinatol. 2012 Sep 1;39(3):525-42.

    AbstractThe electrical activity of the diaphragm (Edi) is measured by a specialized nasogastric/orogastric tube positioned in the esophagus at the level of the crural diaphragm. Neurally adjusted ventilatory assist (NAVA) uses the Edi signal as a neural trigger and intrabreath controller to synchronize mechanical ventilatory breaths with the patient's respiratory drive and to proportionally support the patient's respiratory efforts on a breath-by-breath basis. NAVA improves patient-ventilator interaction and synchrony even in the presence of large air leaks, and might therefore be an optimal option for noninvasive ventilation in neonates.Copyright © 2012 Elsevier Inc. All rights reserved.

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