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Pediatric blood & cancer · Feb 2008
Case ReportsNeuroblastoma presenting with dilated cardiomyopathy.
- M Kato, S Hirata, A Kikuchi, K Ogawa, H Kishimoto, and R Hanada.
- Division of Hematology/Oncology, Saitama Children's Medical Center, Saitama, Japan.
- Pediatr Blood Cancer. 2008 Feb 1;50(2):391-2.
AbstractWe report an infant with neuroblastoma who presented with dilated cardiomyopathy. A 3-month-old girl presented with dilated cardiomyopathy diagnosed as stage III neuroblastoma. Since total resection was impossible, chemotherapy was started. Cardiomyopathy was normalized by improvement of neuroblastoma. The prompt improvement of cardiac function following treatment of neuroblastoma suggested that cardiomyopathy in this patient was caused by the increase in catecholamines secreted by neuroblastoma and that reduction in catecholamines by treatment of neuroblastoma led to improvement in the cardiomyopathy.(c) 2007 Wiley-Liss, Inc.
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