• J. Infect. Dis. · Aug 2015

    Observational Study

    Association of Oseltamivir Treatment With Virus Shedding, Illness, and Household Transmission of Influenza Viruses.

    • Doug H Cheung, Tim K Tsang, Vicky J Fang, Jiajing Xu, Kwok-Hung Chan, Dennis K M Ip, Joseph Sriyal Malik Peiris, Gabriel M Leung, and Benjamin J Cowling.
    • Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.
    • J. Infect. Dis. 2015 Aug 1;212(3):391-6.

    AbstractIn an observational study of 582 patients with laboratory-confirmed influenza virus infections and their household contacts, we found that the initiation of oseltamivir within 24 hours was associated with shorter duration of self-reported illness symptoms (56% reduction in duration; 95% confidence interval, 41%-67%). However, we did not find any association of oseltamivir treatment with duration of viral shedding by polymerase chain reaction or with the risk of household transmission.© The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

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