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- P N Bramley, P Shah, D J Williams, and M S Losowsky.
- Department of Medicine, St. James's University Hospital, Leeds, UK.
- Postgrad Med J. 1989 Sep 1;65(767):687-8.
AbstractA previously fit 56 year old female presented with a rapidly progressive and fatal pneumococcal septicaemia with disseminated intravascular coagulation. Post-mortem studies confirmed a Waterhouse-Friderichsen syndrome and revealed an anatomically normal spleen; intracellular diplococci were seen within splenic macrophages providing evidence of normal splenic function. This appears to be only the second case of Waterhouse-Friderichsen syndrome due to pneumococcal septicaemia in a patient with a normal spleen.
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