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Acta Anaesthesiol Belg · Jan 1988
Clinical Trial Controlled Clinical TrialA new lormetazepam galenical formulation for sublingual premedication.
- M J Van Boven, J L Scholtes, E Collard, L Van Obbergh, and B F Gribomont.
- Department of Anesthesiology, Catholic University of Louvain Medical School, Brussels, Belgium.
- Acta Anaesthesiol Belg. 1988 Jan 1;39(4):233-7.
AbstractThis study reports a double-blind evaluation of a new formulation of lormetazepam for sublingual administration, given as a premedicant in 48 female patients undergoing minor gynecological procedures. Both patient's and nurse's assessments for anxiety and sedation were recorded at different times. Anxiolysis and sedation were present 30 minutes after administration of the drug as reported by the patient with a peak effect at 45 minutes. Nurses reported significant differences in sedation only, but already present at 30 minutes after premedication. The memory test showed no persistent effect of the benzodiazepine one day after surgery.
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