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Eur J Cardiothorac Surg · Nov 2008
Case ReportsUse of Argatroban for anticoagulation during cardiopulmonary bypass in a patient with heparin allergy.
- Alan I Smith, Robert Stroud, Peter Damiani, and Mikhail Vaynblat.
- Division of Cardiothoracic Surgery, Maimonides Medical Center, Brooklyn, NY, NY 11219, USA.
- Eur J Cardiothorac Surg. 2008 Nov 1;34(5):1113-4.
AbstractThe use of Argatroban for treatment of heparin-induced thrombocytopenia (HIT) and for percutaneous coronary intervention in patients with HIT is well described and FDA approved. The use of Argatroban for cardiopulmonary bypass remains off label and the subject of a few case reports. We report the case of a patient with a heparin allergy requiring cardiopulmonary bypass (CPB) for mitral valve replacement. Argatroban was successfully used as anticoagulation for CPB.
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