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Clinics in chest medicine · Sep 2011
ReviewDiagnosis of ventilator-associated respiratory infections (VARI): microbiologic clues for tracheobronchitis (VAT) and pneumonia (VAP).
- Donald E Craven, Jana Hudcova, and Yuxiu Lei.
- Center for Infectious Disease & Prevention, Lahey Clinic Medical Center, Burlington, MA 01805, USA. donald.e.craven@lahey.org
- Clin. Chest Med. 2011 Sep 1;32(3):547-57.
AbstractIntubated patients are at risk of bacterial colonization and ventilator-associated respiratory infection (VARI). VARI includes tracheobronchitis (VAT) or pneumonia (VAP). VAT and VAP caused by multidrug-resistant (MDR) pathogens are increasing in the United States and Europe. In patients with risk factors for MDR pathogens, empiric antibiotics are often initiated for 48 to 72 hours pending the availability of pathogen identification and antibiotic sensitivity data. Extensive data indicate that early, appropriate antibiotic therapy improves outcomes for patients with VAP. Recognizing and treating VARI may allow earlier appropriate therapy and improved patient outcomes.Copyright © 2011 Elsevier Inc. All rights reserved.
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