• Eat Weight Disord · Dec 2008

    Efficacy of inpatient treatment in severely malnourished anorexia nervosa patients.

    • M G Gentile, G M Manna, R Ciceri, and E Rodeschini.
    • Eating Disorders Unit, Niguarda Hospital, Milan, Italy. centrodca@ospedaleniguarda.it
    • Eat Weight Disord. 2008 Dec 1;13(4):191-7.

    ObjectiveOur aim is to present clinical results achieved with an intensive treatment programme for severe anorexia nervosa (AN) patients at risk of severe disability or death. Aims of the treatment are to remove life threatening conditions, physical and nutritional rehabilitation, and psychological and relational rehabilitation.MethodsWe present an observational retrospective study of a cohort of 99 consecutive patients affected by severe AN [according to Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR)] and a body mass index (BMI) ResultsNinety-nine patients affected by severe Protein- Energy-Malnutritrion (PEM) due to AN were eligible in the study. Mean BMI was 12.5+/-0.9 kg/m2, mean age 21.9+/-8.6 yrs. Of 99 patients, 75 (75.5%) completed the planned treatment (completer subgroup). Eighteen patients prematurely interrupted their treatment before achieving complete weight restoration (dropout subgroup); on average they were older and ill for a longer time before admission. Six patients asked to be transferred to other eating disorder units closer to their towns. Seventy-five completer AN patients continued to undergo intensive inpatient treatment till the achievement of BMI 18.3+/-0.8 kg/m2 and then they have been in follow-up outpatient for a mean period of 17.4+/-1.6 months with an average extra increase of their BMI until to 19.1+/-1.6 kg/m2. In 32 patients with a more severe malnutrition we had to resort to nasogastric enteral feeding for 4.4+/-2.5 months, with a mean caloric supply of 1375+/-211 Kcal until the patients were no longer at life risk and they started to co-operate to treatment, increasing oral food amounts.DiscussionOur results seem to provide strong support for using a highly structured program for treating patients with severe AN, including inpatient care and multidisciplinary medical and psychological teams specialized in eating disorder treatment.

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