• J. Child Neurol. · Jan 1991

    Review

    Vigabatrin in refractory epilepsy in adults and its application in children.

    • M Dam.
    • University Clinic of Neurology, Hvidovre Hospital, Denmark.
    • J. Child Neurol. 1991 Jan 1;Suppl 2:S25-9.

    AbstractVigabatrin has been studied in adult drug-resistant epilepsy since 1982 in single-blind and double-blind studies followed by long-term, open evaluations. These studies have provided evidence that vigabatrin is a potent and well-tolerated antiepileptic drug and support its potential value in pediatric epilepsy. The lack of any evidence of human neurotoxicity in these patients is also reassuring regarding its use in children.

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