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Comparative Study
[Experience in postoperative sedation with dexmedetomidine for mandibular osteotomy].
- Miho Maeda, Haruo Fukuyama, Satoko Ando, and Toshiyasu Suzuki.
- Department of Anesthesiology, University of Tokai School of Medicine, Isehara 259-1193.
- Masui. 2007 Aug 1;56(8):942-4.
BackgroundDexmedetomidine may be suitable for postoperative sedation of patients with mandibular osteotomy.MethodsTwenty patients were sedated with dexmedetomidine (group D) employing loading infusion at 1.0 microg x kg(-) x hr(-1) and then continuous infusion at 0.7 mg x kg(-1) x hr(-1). Other twenty patients were sedated with midazolam 0.1 mg x kg(-1) (group C). Ramsay score was recorded at 3 hours and 12 hours after infusing sedative drugs. Then, we questioned patients, nurses and doctors.ResultsRamsay score in the group D was higher than that in the group C (P < 0.01). Hypotension and respiratory depression did not occur. But bradycardia occurred in two cases. By adding propofol, group D showed more effective sedation.ConclusionsThis study shows that sedation with dexmedetomidine is more suitable than that with midazolam.
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