• Psychological medicine · Mar 2007

    Randomized Controlled Trial Multicenter Study

    Cognitive self-therapy for chronic depression and anxiety: a multi-centre randomized controlled study.

    • Peter C A M den Boer, Durk Wiersma, Inge Ten Vaarwerk, Mark M Span, A Dennis Stant, and Robert J Van den Bosch.
    • Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands. p.c.a.m.den.boer@psy.umcg.nl
    • Psychol Med. 2007 Mar 1;37(3):329-39.

    BackgroundNon-professional treatment programmes are presumed to relieve the extensive need for care of anxiety and depression disorders. This study investigates the effectiveness of cognitive self- therapy (CST) in the treatment of depression or generalized anxiety disorder.MethodPatients (n=151) were randomized to receive CST or treatment as usual (TAU) in a trial lasting for 18 months, measuring symptoms (SCL-90; main outcome), social functions, quality of life and utilization of care.ResultsPatients in both conditions improved significantly, but no difference was found between the conditions. Reduction of symptoms, improvement of social functions and medical utilization were maintained at the end of the 18 months. Medical care utilization (therapist contact and hospitalization) was lower for CST than for TAU. No suicides occurred.ConclusionsCognitive self-therapy is likely to decrease the need for care of chronic depression and anxiety disorders, but it has not been proven to be more effective than treatment as usual.

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