• E Kilger, J Briegel, M Haller, T Hummel, J Groh, H Dienemann, A Welz, and H Forst.
• Institut für Anästhesiologie, Ludwig-Maximilians-Universität München, Klinikum Grosshadern.
• Med Klin. 1995 Apr 1;90(1 Suppl 1):26-8.

BackgroundNon-invasive mechanical ventilation (NIPPV) is an accepted choice of treatment in patients with chronic pulmonary disease and/or acute respiratory failure. Recently NIPPV was also proposed in the postoperative weaning period.Patients And MethodsSix of 30 patients after lung transplantation were were extubated despite a weaning failure was predicted using well accepted weaning criteria. Therefore, the 6 patients were treated with intermittent-noninvasive ventilation using assisted modes of mechanical ventilation (PSV/CPAP).ResultsBoth, oxygenation (increase in paO2: 18 mm Hg during PSV, 11 mm Hg during CPAP) and pulmonary mechanics (decrease in respiratory rate: 14/min during PSV, 10/min during CPAP; increase in tidal volume: 5 ml/kg during PSV, 3 ml/kg KG during CPAP) improved and the energy expenditure decreased (19% during PSV, 12% during CPAP).ConclusionNon-invasive ventilation after lung transplantation enables earlier extubation and prevents weaning failure.

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