• Surgical innovation · Sep 2005

    Comparative Study

    Small intestinal submucosa intracardiac patch: an experimental study.

    • Michael Rosen, Eric E Roselli, Cristiano Faber, Norman B Ratliff, Jeffrey L Ponsky, and Nicholas G Smedira.
    • Cleveland Clinic Foundation Department of General Surgery, Cleveland, OH 44195, USA.
    • Surg Innov. 2005 Sep 1;12(3):227-31.

    AbstractIn this experimental study, small intestinal submucosa was implanted as an atrial prosthesis in calves. Echocardiography and histology showed this to be an impermeable prosthesis that develops a neointimal nonthrombogenic surface making it safe for repair of defects in a low-pressure system. Further study with small intestinal submucosa in an intracardiac position is warranted.

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