• Medicina intensiva · Jan 2014

    Review

    Indications of dexmedetomidine in the current sedoanalgesia tendencies in critical patients.

    • M A Romera Ortega, C Chamorro Jambrina, I Lipperheide Vallhonrat, and I Fernández Simón.
    • Servicio de Medicina Intensiva, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, España.
    • Med Intensiva. 2014 Jan 1;38(1):41-8.

    AbstractRecently, dexmedetomidine has been marketed in Spain and other European countries. The published experience regarding its use has placed dexmedetomidine on current trends in sedo-analgesic strategies in the adult critically ill patient. Dexmedetomidine has sedative and analgesic properties, without respiratory depressant effects, inducing a degree of depth of sedation in which the patient can open its eyes to verbal stimulation, obey simple commands and cooperate in nursing care. It is therefore a very useful drug in patients who can be maintained on mechanical ventilation with these levels of sedation avoiding the deleterious effects of over or infrasedation. Because of its effects on α2-receptors, it's very useful for the control and prevention of tolerance and withdrawal to other sedatives and psychotropic drugs. The use of dexmedetomidine has been associated with lower incidence of delirium when compared with other sedatives. Moreover, it's a potentially useful drug for sedation of patients in non-invasive ventilation.Copyright © 2013 Elsevier España, S.L. y SEMICYUC. All rights reserved.

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