• Kosuke Akiyama, Masayuki Karaki, Masafumi Yonezaki, Rieko Goto, Rhyuhei Inamoto, Hiroshi Hoshikawa, and Nozomu Mori.
• Department of Otolaryngology, Mitoyo General Hospital, Mitoyo-shi, Toyohama-cho, Himehama 708, Kagawa 769-1695, Japan; Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan. Electronic address: kakaka@med.kagawa-u.ac.jp.
• Auris Nasus Larynx. 2014 Jun 1;41(3):264-8.

ObjectiveSilver-containing carboxymethylcellulose fiber dressing (Aquacel®-Ag) has been used to treat burns and ulcers with a large amount of exudate. The aim of this investigation was to confirm whether Aquacel®-Ag has beneficial effects when it is used as nasal packing.MethodsWe included 44 patients who underwent bilateral endoscopic sinus surgery due to chronic rhino-sinusitis. Beschitin-F® or Aquacel®-Ag was packed postoperatively into the bilateral middle meatus. Patient's comfort was recorded using a VAS, as well as wound healing, postoperative bleeding and local infection. Postoperative-specific organisms were also evaluated from the removed packing materials located in the middle meatus when they were removed on the 4th day after surgery.ResultsThe scores for nasal obstruction and pain were not statistically different in each group. Postoperative bacteriologic studies indicated marked differences. Coagulase-negative staphylococci were predominant and potential pathogens were recovered in a few cases in the Aquacel®-Ag group. In contrast, potential pathogens, including Streptococcus pneumonia, Haemophilus influenza, and Gram-negative rods, were predominant in the Beschitin-F® group.ConclusionThe results indicate that Aquacel®-Ag might contribute to hemostasis, wound healing, and patient comfort after endonasal surgery, similar to Beschitin-F®. Additionally, it may have advantages concerning the prevention of postoperative infection.Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

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