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- Jens Bjerregaard and Richard A Jaffe.
- Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305, USA.
- J Clin Anesth. 2014 Feb 1;26(1):62-4.
AbstractContinuing renin-angiotensin-aldosterone system antagonist therapy on the day of surgery is controversial, and appears to contribute to intraoperative hypotension. A patient presenting for cerebral aneurysm clipping continued her angiotensin-converting enzyme inhibitor on the morning of surgery, and subsequently experienced significant postinduction hypotension that culminated in cardiac arrest. Following successful resuscitation, she returned 6 weeks later to have her aneurysm clipped using identical anesthetic management; her blood pressure medications were held on the day of surgery.Copyright © 2014 Elsevier Inc. All rights reserved.
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