• J Med Assoc Thai · May 2014

    Randomized Controlled Trial

    Oral rehydration with 10% carbohydrate drink for preventing postoperative nausea and vomiting (PONV) after low dose of spinal morphine.

    • Manee Raksakietisak, Tithima Chinachoti, Arissara Iamaroon, Yos Thabpenthai, Pathom Halilamien, Sasiya Siriratwarangkul, and Arraya Watanitanon.
    • J Med Assoc Thai. 2014 May 1;97(5):530-5.

    BackgroundPreoperative oral carbohydrate (CHO) drink may improve patients' comfort. However, whether it prevents or reduces postoperative nausea and vomiting (PONV) is questionable.ObjectiveEvaluate the effect of oral rehydration with 10% CHO drink before anesthesia on incidence and severity of postoperative nausea and vomiting (PONV) after spinal morphine injection.Material And MethodOne hundred patients scheduled for unilateral total knee replacement (TKR) were randomly divided into two equal groups (n = 50 each). Group I patients received 400 ml 10% CHO drink the preoperative night and 2-hour before anesthesia, whereas Group II patients served as control. Spinal anesthesia for all patients contained 0.5% bupivacaine 2.0 to 3.5 ml plus morphine 0.2 mg. Pain therapy was standardized with femoral nerve block, local infiltration, intravenous parecoxib, and oral paracetamol. Incidence and severity of PONV within 24 hours were recorded In addition, preoperative intensity of thirst and hunger, dry lips and throat, and anxiety was also recordedResultsIncidence and severity of PONV (81.2% vs. 72.0%, p = 0.536) as well as preoperative thirst, hunger dry lips, and throat were not different between the groups.ConclusionPreoperative oral rehydration with carbohydrate drinks had no positive effect on PONV nor patients' comfort.

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