• A Scott Keller, Lisa L Kirkland, Smita Y Rajasekaran, Stephen Cha, Mohamed Y Rady, and Jeanne M Huddleston.
• Division of Hospital Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA. keller.scott@mayo.edu
• J Hosp Med. 2010 Oct 1;5(8):460-5.

BackgroundUnplanned (unexpected) transfers to the intensive care unit (ICU) are typically preceded by physiologic instability. However, trends toward instability may be subtle and not accurately reflected by changes in vital signs. The shock index (SI) (heart rate/systolic blood pressure as an indicator of left ventricular function, reference value of 0.54) may be a simple alternative means to predict clinical deterioration.ObjectiveTo assess the association of the SI with unplanned ICU transfers.DesignRetrospective case-control study.SettingAcademic medical center.PatientsFifty consecutive general medical patients with unplanned ICU transfers between 2003 and 2004 and 50 matched controls admitted to the same general medical unit between 2002 and 2004.MeasurementsDemographic data and vital signs abstracted from chart review.ResultsThe SI was associated with unplanned ICU transfer at values of 0.85 or greater (P < 0.02; odds ratio, 3.0) and there was a significant difference between the median of worst shock indices of cases and controls (0.87 vs. 0.72; P < 0.005). There was no significant difference in age, race, admission ward, or Charlson Comorbidity Index, but hospital stay for cases was significantly longer (mean [standard deviation, SD], 14.8 [9.7] days vs. 5.7 [6.3] days; P < 0.001).ConclusionsSI is associated with unplanned transfers to the ICU from general medical units at values of 0.85 or greater. Future studies will determine whether SI is more accurate than simple vital signs as an indicator of clinical decline. If so, it may be a useful trigger to activate medical emergency or rapid response teams (RRTs).

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