• Ann. Thorac. Surg. · Dec 2002

    Case Reports

    Anticoagulation with bivalirudin during cardiopulmonary bypass in cardiac surgery.

    • Julio C Vasquez, Anna Vichiendilokkul, Syed Mahmood, and Frank A Baciewicz.
    • Department of Cardiothoracic Surgery, Harper University Hospital, Wayne State University, Detroit, Michigan 48201, USA.
    • Ann. Thorac. Surg. 2002 Dec 1;74(6):2177-9.

    AbstractHeparin is the standard agent used for systemic anticoagulation during cardiopulmonary bypass in cardiac operations. Alternatives are needed when patients with heparin-induced thrombocytopenia type II are encountered. We present a patient with a clinical picture of heparin-induced thrombocytopenia type II who was effectively anticoagulated with bivalirudin, a direct thrombin inhibitor, during cardiopulmonary bypass for a cardiac operation.

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