• Clinics in perinatology · Mar 2006

    Review

    Naloxone during neonatal resuscitation: acknowledging the unknown.

    • Ruth Guinsburg and Myra H Wyckoff.
    • Department of Pediatrics, Division of Neonatal Medicine, Federal University of São Paulo, Rua Vicente Félix 77/09, São Paulo, SP 01410-020, Brazil. ruthgbr@netpoint.com.br
    • Clin Perinatol. 2006 Mar 1;33(1):121-32, viii.

    AbstractThere are no studies to support or to refute the current recommendations regarding naloxone concentration, routes for administration, and doses in neonatal resuscitation in the delivery room. Given the lack of supporting evidence, naloxone should not be given routinely in the delivery room to depressed neonates whether or not they are exposed to opioids before delivery because no important improvement has been documented and the drug may have potential short- and long-term harmful effects.

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