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Pediatric cardiology · Sep 2007
Case ReportsUse of dexmedetomidine in patients with trisomy 21 after cardiac surgery.
- M Kalyanaraman, J L Costello, and J P Starr.
- Children's Hospital of New Jersey, C-5, 201 Lyons Avenue, Newark, NJ 07112, USA. mkalyanaraman@sbhcs.com
- Pediatr Cardiol. 2007 Sep 1;28(5):396-9.
AbstractChildren with trisomy 21 have a high incidence of congenital heart disease that frequently requires surgical repair. These patients often require multiple and higher dosage sedatives during the postoperative period. Dexmedetomidine is an alpha(2)-adrenergic receptor agonist that has sedative, analgesic, and anxiolytic properties. We report the successful use of dexmedetomidine in patients with trisomy 21 following surgical repair of congenital heart disease.
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