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Clinics in perinatology · Jun 2001
ReviewPrenatal diagnosis using fetal cells and free fetal DNA in maternal blood.
- W Holzgreve and S Hahn.
- Department of Obstetrics and Gynecology, University of Basel, Basel, Switzerland. wholzgreve@uhbs.ch
- Clin Perinatol. 2001 Jun 1;28(2):353-65, ix.
AbstractThe presence of fetal cells and free fetal DNA in maternal blood offers an exciting opportunity for the development of safe noninvasive forms of prenatal diagnosis. Research in this field has, however, also indicated that their levels in the maternal circulation are increased in certain pregnancy-related disorders, such as preeclampsia. Their closer examination may shed new light on the underlying etiology of this enigmatic disorder.
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