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- Laurence Senn, Mario Franciolli, Didier Raoult, Alexandre Moulin, Ludwig Von Segesser, Thierry Calandra, and Gilbert Greub.
- Infectious Diseases Service, Department of Internal Medicine, University Hospital, Lausanne, Switzerland. Laurence.Senn@chuv.ch
- Bmc Infect Dis. 2005 Jan 1;5:109.
BackgroundCoxiella burnetii, the causative agent of Q fever, may cause culture-negative vascular graft infections. Very few cases of C. burnetii infection of a vascular graft have been reported. All were diagnosed by serology.Case PresentationWe report the first case of Coxiella burnetii vascular graft infection diagnosed by broad-range PCR and discuss the diagnostic approaches and treatment strategies of chronic C. burnetii infection.ConclusionC. burnetii should be considered as etiological agent in patients with a vascular graft and fever, abdominal pain, and laboratory signs of inflammation, with or without exposure history. Broad-range PCR should be performed on culture-negative surgical samples in patients with suspected infection of vascular graft.
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