• Med Klin · Sep 1997

    [Selenium, antioxidant status and radical/reactive oxygen species in medicine].

    • K Winnefeld.
    • Institut für Klinische Chemie, Friedrich-Schiller-Universität, Jena.
    • Med Klin. 1997 Sep 15;92 Suppl 3:8-10.

    BackgroundIn all organisms with a metabolism of oxygen, radicals/reactive oxygen species appear. Normally a balance exists between formation and destruction of radicals. Many diseases show a disturbance of this balance with the destruction of biological structures. Results in patients with sepsis, terminal renal failure, bone marrow transplantation and cancer are given.ConclusionTo avoid a possible pro-oxidative effect (vitamins C and E) and intoxications (selenium), before substitution a monitoring is necessary.

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