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Case Reports
Massive pulmonary embolism in pregnancy treated with catheter-directed tissue plasminogen activator.
- Jeremy Pick, David Berlin, James Horowitz, Ron Winokur, Akhilesh K Sista, and Adam D Lichtman.
- From the Departments of *Anesthesiology, †Medicine, and ‡Radiology, New York Presbyterian Medical Center, Weill Medical College of Cornell University, New York, New York.
- A A Case Rep. 2015 Apr 1; 4 (7): 91-4.
AbstractPulmonary embolism is a leading cause of maternal death in the United States, contributing to the death of approximately 2 women per 100,000 live births each year. Thrombosis during pregnancy traditionally is treated conservatively with unfractionated heparin or low-molecular-weight heparin; however, cardiovascular collapse associated with a large pulmonary embolus may require immediate aggressive intervention to save the mother and fetus. We report the use of catheter infusion thrombolysis in the successful management of a third-trimester pregnant patient with a hemodynamically significant saddle pulmonary embolus.
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