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The Journal of infection · Jan 2014
ReviewAdvances towards the prevention of meningococcal B disease: a multidimensional story.
- Marion Roderick and Adam Finn.
- Bristol Royal Hospital for Children, Bristol, UK. Electronic address: Marion.Roderick@UHBristol.nhs.uk.
- J. Infect. 2014 Jan 1;68 Suppl 1:S76-82.
AbstractWhilst much progress has been made in reducing the burden of bacterial meningitis and septicaemia through vaccination, endemic serogroup B meningococcal (MenB) disease has remained problematic. Polysaccharide-protein conjugate vaccines are now available to protect against Haemophilus influenzae type b, Neisseria meningitidis serogroups A, C, Y and W and thirteen serotypes of Streptococcus pneumoniae, but this approach has not been used for MenB. Instead efforts have been made to identify protein antigens which, when used in vaccines, will prevent MenB infection and possibly disease due to other serogroups too. The first such vaccine has recently been licensed.Copyright © 2013 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
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