• A & A case reports · Jan 2016

    Case Reports

    Symptoms of Central Anticholinergic Syndrome After Glycopyrrolate Administration in a 5-Year-Old Child.

    • Linea Natalie Toksvang and Ronni R Plovsing.
    • From the *Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark; †Department of Anaesthesiology, Køge Sygehus, Køge, Denmark; and ‡Department of Intensive Care, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
    • A A Case Rep. 2016 Jan 15; 6 (2): 22-4.

    AbstractAnesthesia-related central anticholinergic syndrome (CAS) is most commonly associated with administration of atropine or scopolamine, whereas glycopyrrolate is an extremely rare cause of CAS. Here, we report a case of CAS in a 5-year-old boy admitted to the intensive care unit. Immediately after the administration of glycopyrrolate, he became agitated and developed apnea, hypertension, tachycardia, and anuria. Although the present case describes a rare cause of CAS, it is an important reminder of an iatrogenic condition that is presumably underdiagnosed in the operating theater as well as the intensive care unit.

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