• Surg J R Coll Surg E · Apr 2010

    Review

    Known knowns, known unknowns and unknown unknowns: a 2010 update on carotid artery disease.

    • A Ross Naylor.
    • Department of Vascular Surgery, Clinical Sciences Building, Leicester Royal Infirmary, Leicester, UK. ross.naylor@uhl-tr.nhs.uk
    • Surg J R Coll Surg E. 2010 Apr 1;8(2):79-86.

    AbstractThe management of carotid artery disease never ceases to attract controversy. The last 12 months has seen publication of a number of important studies which have informed debate and 2010 holds the prospect of much more. This update offers a personal review of a number of contemporary issues including; (i) guidelines for non-invasive imaging in rapid access clinics, (ii) whether improvements in best medical therapy have rendered many of the conclusions from ACAS and ACST obsolete, (iii) is carotid disease really just a marker for increased stroke risk following cardiac surgery (rather than being an important cause), (iv) what is the current status of endarterectomy and stenting in patients with symptomatic carotid disease and (v) why we must offer expedited interventions to TIA/minor stroke patients. The available evidence suggests that while most 'known knowns' will endure, quite a few may be returning to the category of 'known unknowns' once again. Who knows what 'unknown unknowns' await us in 2010 and beyond.Copyright 2010 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

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