• J Med Assoc Thai · Jul 2013

    The sensitivity and specificity of a urine leukocyte esterase dipstick test for the diagnosis of urinary tract infection in the outpatient clinic of Rajavithi Hospital.

    • Sirirat Laosu-angkoon.
    • Department of Outpatient Clinic, Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand. swuuerm@hotmail.com
    • J Med Assoc Thai. 2013 Jul 1;96(7):849-53.

    BackgroundUrinary tract infection (UTI) is frequentlyfound in family physician clinics. The present study was designed to assess the reliability of a leukocyte esterase urine dipstick test in detecting UTI.ObjectiveCompare the performance and reliability ofleukocyte esterase dipstick urinalysis with microscopic examination for detection of clinically suspected UTI.Material And MethodA retrospective descriptive study was conducted on 109 patients who visited the outpatient clinic with a clinical suspicion of UTI between November 2010 and July 2011. The subjects consisted ofpatients from the age of 15 years and over regardless of gender A dipstick test (Combur-Test Mstrip, Roche) was used. All dipstick-positive samples were processed to microscopic examination and urine culture was used as gold standard. Sensitivity, specificity, and predictive values were analyzed for the dipstick test (leukocyte esterase) as compared to microscopic examination. Statistical analysis was performed by using the t-test.ResultsThe sensitivity of leukocyte esterase test and the combined leukocyte esterase and nitrite test were 63.6% and 66.7%, respectively. The presence of pyuria demonstrated the highest sensitivity (95.6%) and specificity (60.9%) for positive urine culture compared to the dipstick test. Statistical analysis revealed a significant correlation between the dipstick test (leukocyte esterase) and microscopic examination (p< 0. 001).ConclusionPyuria can be used to detect UTI instead of urine culture due to its significant incidence. In the present study, the presence of pyuria had a higher specificity (60.9%) compared to the dipstick test (44.2%). However the significantly positive dipstick and pyuria results make the combined test more useful than the single test, and there is a statistically significant correlation between the dipstick test (leukocyte esterase) and the microscopic examination (p< 0. 001). Therefore, the dipstick test (leukocyte esterase) can be used as a diagnostic tool in detecting UTI cases.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…