• La Clinica terapeutica · Jan 2012

    Review

    Role of noninvasive ventilation in elderly patients with hypercapnic respiratory failure.

    • G G Riario-Sforza, P Scarpazza, C Incorvaia, and W Casali.
    • Pulmonary Rehabilitation, ICP Hospital, Milan, Italy.
    • Clin Ter. 2012 Jan 1;163(1):e47-52.

    AbstractThe effectiveness of non-invasive ventilation (NIV) in treating patients with acute respiratory failure (ARF) is showed by its ability to diminish the recurrence to endotracheal intubation (ETI), the occurrence of ETI-associated lung infections as well as related mortality. A specific issue is the outcome of NIV in patients referring to Emergency Department for ARF who receive a do-not-intubate (DNI) order because of too critical conditions or advanced age. Recent data show that elderly patients (mean age 81 years) with ARF who have a DNI order can be successfully treated by NIV, as demonstrated by a survival rate of 83%. The positive outcome was confirmed by a subsequent 3-year observation, that demonstrated an overall survival rate of 54%. These findings clearly suggest to treat by NIV elderly patients also in presence of a DNI order.

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