• Clinics in chest medicine · Dec 2013

    Review

    Novel medical therapies for pulmonary arterial hypertension.

    • Caroline O'Connell, Dermot S O'Callaghan, and Marc Humbert.
    • Department of Respiratory Medicine, Mater Misericordiae University Hospital, 56 Eccles Street, Dublin 7, Ireland. Electronic address: caroline1597@hotmail.com.
    • Clin. Chest Med. 2013 Dec 1;34(4):867-80.

    AbstractAvailable targeted therapies for pulmonary arterial hypertension are capable only of slowing progression of the disease and a cure remains elusive. However with the improved understanding of the pulmonary vascular remodeling that characterizes the disease, there is optimism that the disconnect between preclinical and clinical studies may be bridged with some of the newer therapies that are now at different stages of clinical evaluation. This article examines the evidence behind these new candidate treatments that may become part of the arsenal available for clinicians managing this devastating disease.Copyright © 2013 Elsevier Inc. All rights reserved.

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