• Clinics in perinatology · Dec 2009

    Review

    Advances in near-infrared spectroscopy to study the brain of the preterm and term neonate.

    • Martin Wolf and Gorm Greisen.
    • Biomedical Optics Research Laboratory, Clinic of Neonatology, University Hospital Zurich, Frauenklinikstr. 10, 8091 Zurich, Switzerland. martin.wolf@usz.ch
    • Clin Perinatol. 2009 Dec 1;36(4):807-34, vi.

    AbstractThis article reviews tissue oximetry and imaging to study the preterm and newborn infant brain by near-infrared spectroscopy. These two technologies are now advanced; nearly 100 reports on their use in newborn infants have been published, and commercial instruments are available. The precision of oximetry, however, is a limitation for its clinical use of assessing cerebral oxygenation. Imaging of brain function needs very well defined protocols for sensory stimulation as well as signal analysis to provide meaningful results.

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