Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal

J. Clin. Microbiol. · Jun 2008

Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal transplant unit.

We describe a Klebsiella oxytoca infection outbreak in a renal transplant unit that involved seven patients. All strains belonged to a single pulsed-field gel electrophoresis pattern and were resistant to amoxicillin-clavulanate, cefuroxime, piperacillin-tazobactam, and aztreonam but susceptible to ceftriaxone, ceftazidime, cefepime, and imipenem. Chromosomal beta-lactamase hyperproduction was caused by a point mutation in the bla(OXY-2) gene promoter region.

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- Mariela Soledad Zárate, Ana C Gales, Renata C Picão, Gervasio Soler Pujol, Alejandra Lanza, and Jorgelina Smayevsky.
- Laboratorio de Bacteriología, Micología y Parasitología, Sección de Nefrología, Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno CEMIC, Ciudad Autónoma de Buenos Aires, Argentina. sole_z@hotmail.com
- J. Clin. Microbiol. 2008 Jun 1;46(6):2099-101.
AbstractWe describe a Klebsiella oxytoca infection outbreak in a renal transplant unit that involved seven patients. All strains belonged to a single pulsed-field gel electrophoresis pattern and were resistant to amoxicillin-clavulanate, cefuroxime, piperacillin-tazobactam, and aztreonam but susceptible to ceftriaxone, ceftazidime, cefepime, and imipenem. Chromosomal beta-lactamase hyperproduction was caused by a point mutation in the bla(OXY-2) gene promoter region.

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Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal transplant unit.

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