• La Revue du praticien · Mar 2008

    Review

    [Pulmonary manifestations of the vasculitides].

    • Jean-François Cordier.
    • Service de pneumologie, Centre de référence des maladies orphelines pulmonaires, hôpital Louis-Pradel, Lyon. jean-francois.cordier@chu-lyon.fr
    • Rev Prat. 2008 Mar 15;58(5):492-8.

    AbstractThe vasculitides involving the lower respiratory tract are mainly the small vessels vasculitides associated with antineutrophil cytoplasmic autoantibodies including Wegener granulomatosis (WG), microscopic polyangiitis (MPA), and Churg-Strauss syndrome (SCS). WG pulmonary manifestations mainly consist of nodules and pneumonias often cavitary, and tracheobronchial stenoses. MPA often consists of pulmonary-renal syndrome with alveolar hemorrhage possibly severe. In SCS, asthma with eosinophilia and further eosinophilic pneumonia are the characteristic pulmonary features. Lung biopsy may be necessary in WG to obtain a definite diagnosis when no other site for biopsy is possible.

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