• Pediatric emergency care · Aug 2010

    Case Reports

    Reversal of intractable hypoxemia with exogenous surfactant (calfactant) facilitating complete neurological recovery in a pediatric drowning victim.

    • Brian Michael Varisco, Crystal Marie Palmatier, and Jeffrey Allen Alten.
    • Division of Pediatric Critical Care Medicine and daggerDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA. bvarsico@peds.uab.edu
    • Pediatr Emerg Care. 2010 Aug 1; 26 (8): 571-3.

    ObjectiveTo report the successful reversal of intractable hypoxemia after exogenous surfactant (calfactant) administration, facilitating neurological recovery in a toddler cold-water drowning victim with significant circulatory arrest time.MethodsCase report and review of literature.ResultsA 2(1/2)-year-old girl cold-water drowning victim with severe, intractable hypoxemia after submersion time of approximately 15 minutes and arrest time of approximately 45 minutes was given 80 mL/m of calfactant endotracheally with reversal of her hypoxemia and eventual neurologically intact survival.ConclusionsSurfactant replacement with calfactant is a rational, useful, and potentially lifesaving treatment for acute hypoxemic respiratory failure due to drowning.

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