• Joong Ho Ahn and Myung Joo Shim.
• Department of Otolaryngology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea. meniere@amc.seoul.kr
• Auris Nasus Larynx. 2013 Feb 1;40(1):7-10.

ObjectiveTo evaluate the anti-adhesive and anti-inflammatory effects of sodium hyaluronate-carboxymethylcellulose (HA-CMC) in reducing postoperative pain after temporalis fascia harvest during tympanomastoid surgery.Materials And MethodsBetween January and December 2009, 27 patients underwent tympanoplasty and open cavity mastoidectomy involving the harvesting of temporalis fasciae (more than 3×4cm). At the end of surgery, patients were injected with 1.5g HA-CMC or normal saline around the fascia harvest area. Beginning immediately postoperatively and for 2 months after surgery, patients scored their pain in the temporal area on a visual analogue scale (VAS).ResultsThere were no significant postoperative complications, such as bleeding or hematoma, in either control group. VAS scores of both groups decreased over time and were negligible after 2 months. VAS scores of the HA-CMC and control groups differed significantly (p<0.001 by repeated measures ANOVA for all VAS scores).ConclusionHA-CMC can decrease immediate postoperative pain arising from tissue adhesion and inflammation, thus reducing postoperative mastication pain.Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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