• Seminars in nephrology · Mar 2000

    Review

    Kidney-pancreas transplantation for diabetic nephropathy.

    • D E Hricik.
    • Department of Medicine, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, OH 44106, USA.
    • Semin. Nephrol. 2000 Mar 1;20(2):188-98.

    AbstractPancreas transplantation is being performed with increasing frequency and increasing technical success. The availability of new immunosuppressant agents has been associated with a reduction in the previously high rates of allograft rejection in recipients of simultaneous pancreas-kidney transplants. These lower rejection rates have, in turn, led to changes in surgical techniques and a resurgence of interest in isolated pancreas transplantation--either in nonuremic patients or, more commonly, in patients who have already received a prior kidney transplant. Pancreas transplantation has emerged as an important option for the management of patients with type I diabetes mellitus and diabetic nephropathy.

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