[Antiangiogenic agents: current limits in thoracic oncology].

Bulletin du cancer · Nov 2012

Review

[Antiangiogenic agents: current limits in thoracic oncology].

Antiangiogenic agents appear as major therapeutic options in renal, colorectal and breast cancer. Their part in thoracic oncology is still limited today except for bevacizumab. We review the current limits of antiangiogenic agents in terms of efficacy, activity, tolerance and therapeutic strategies. Problems about predictive biomarkers and cost-effectiveness of antiangiogenic agents in thoracic oncology are also mentioned.

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- Eric Dansin, Géraldine Lauridant, and Bachar Chahine.
- CLCC Oscar-Lambret, département de cancérologie générale, Lille Cedex, France. e-dansin@o-lambret.fr
- Bull Cancer. 2012 Nov 1;99(11):1083-91.
AbstractAntiangiogenic agents appear as major therapeutic options in renal, colorectal and breast cancer. Their part in thoracic oncology is still limited today except for bevacizumab. We review the current limits of antiangiogenic agents in terms of efficacy, activity, tolerance and therapeutic strategies. Problems about predictive biomarkers and cost-effectiveness of antiangiogenic agents in thoracic oncology are also mentioned.

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